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Description

(2020) 106:589.e606.e

EBV plays a central etiological role, with viral proteins EBNA1 and LMP1 detected in over 90% of NPC cases and high viral loads correlating with disease progression, from 1,200 copies/ml in early stages to 18,500 copies/ml in advanced stages [3,9]

10.1016/j.ccm.2016.11.011 29

Moreover, they are more likely to display elevated levels of biomarkers associated with systemic inflammation, such as high-sensitivity C-reactive protein (hs-CRP), fibronectin, TNF-, and IL-8 (144147)