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2 or ubiquinol, which acts as a lipophilic radical-trapping antioxidant that can effectively interrupt the lipid peroxidation chain reaction, thus establishing a defense line on the plasma membrane independent of the GPX4GSH system (Mao et al., 2021

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However, while CR has extended the lifespan of certain primates like gray mouse lemurs, it has also been linked to accelerated loss of gray matter in the brain, suggesting possible detrimental effects on brain integrity (Pifferi et al

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