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Diabetes Prevention Program was based on a major clinical trial showing that lifestyle changessuch as increased physical activity and healthier eatingcould reduce diabetes risk by up to 58% and lower cardiovascular disease risk factors, along with decreasing reliance on medications []

These results support that the treatment impacts transcriptional programs by directly targeting VEGF and lowering GFAP levels associated with glial differentiation

The individualized dietary approach, emphasizing a variety of whole foods such as non-starchy vegetables, high-quality proteins, and satiating fats, contributed to a 75% retention rate at six months, surpassing typical adherence rates observed in dietary interventions within oncology populations [140]