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This increased conversion promotes the flux of the TCA cycle to meet the synthetic and metabolic demands of tumor cells and simultaneously regulates serine hydroxymethyltransferase 1 (SHMT1) activity to promote the serineglycine metabolic axis and one-carbon unit supply

Excessive alcohol consumption results in a range of alcoholic liver disease (ALD), from simple alcoholic fatty liver to advanced alcoholic hepatitis, cirrhosis, and eventually hepatocellular carcinoma [2]

This time the deletions are internal deletions so that there are no bases on the 5 or 3 of the subject sequence which are not matched/aligned with the query

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