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Additionally, co-transplantation with stroma can selectively influence the expression of homing receptors and ultimately improve engraftment, as hematopoietic activity increases considerably after stromal establishment (Flake and Zanjani, 2016)

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Furthermore, according to a randomized trial conducted in a population of patients with T2D receiving metformin for at least 4 years and experiencing diabetic neuropathy, administration of 1 mg oral methylcobalamin for 1 year was associated with a significant improvement in neurophysiological parameters and scores assessing neuropathic pain and quality of life [58]

[Google Scholar] 51.Bona E., Hagberg H., Lberg E.M., Bgenholm R., Thoresen M