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AMPK activation, in turn, suppresses ferroptosis by inhibiting PUFA biosynthesis through phosphorylation of acetyl-CoA carboxylase 109

The 12-month trial design enables us to assess senolytic-associated changes before and after treatment during the 3-month active treatment phase, track the reappearance of senescent cells after their removal during the 9-month post-treatment period, and evaluate disease trajectory differences over a one-year period (Figure 3)

Glutathione, often referred to as the master antioxidant, plays a vital role in cellular health and detoxification

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