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Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system

When extracellular Cu 2+ enters the mitochondrial compartment of cells, FDX1 reduces Cu 2+ to Cu + , resulting in the oligomerization of DLAT protein and the downregulation of Fe-S cluster protein expression

As previously noted, studies have employed varying dosages, such as 25 g, 0.2 g, and 8 mg/mL, in animal models, yielding inconsistent effects on tendon regeneration