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UV irradiation induces DNA damage that can lead to nucleotide alterations and beneficial mutations (Lawrence et al., 1982)

Preliminary results show that AAV1-hOTOF gene therapy is safe and effective in improving hearing and speech perception in these children [75]

In spite of 40 years of research the exact function of this protein is more complex than ever, but it has been found that these intracellular dimeric proteins, play a major role in the intracellular transport of endogenous compounds, metabolizes various electrophilic xenobiotics, ligand transport and thus protects cells against toxic effects [31], [87], [85]

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