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10.1172/JCI20039 J Clin Investig

Glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), amylin, glucagon and ghrelin all proved to be tractable drug targets, and mapping how they regulate hunger and energy use produced today's obesity drugs (PMID 34067710)

Excessive ROS production is a major pathological mechanism of neurodegenerative diseases, and IF protects neurons by activating the Nrf2 signaling pathway, increasing the expression of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and reducing ROS accumulation (27)