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doi: 10.1016/j.bbrc.2013.04.047 44 PearceELPearceEJ

The European respiratory journal , 58 (1), 2101090

Although the capacity for metabolism within neutrophils is dwarfed by hepatic metabolism, it is thought to be important for localized reactive metabolite generation, and provides an explanation for the formation of extra-hepatic adducts with metabolites too unstable to escape the liver [133]