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Mitochondrial Localization of PARP1 Requires Interaction With Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity. Journal of Biological Chemistry 284, no

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), developed by the American Psychiatric Association, defines AUD as a cluster of behavioral and physical symptoms, including withdrawal, tolerance, and craving (American Psychological Association, 2013)

IL-6 and TNF- are representative pro-inflammatory cytokines that amplify epithelial damage, promote immune cell recruitment, and drive the progression of radiation-induced proctitis

Despite these protective functions, it has been demonstrated that MTs are involved in tumorigenesis, cellular differentiation, drug resistance, and metabolic disorders such as diabetes and obesity, in which MTs expression is substantially deregulated in adipose tissue