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The depletion of SCFAs compromises antioxidant defenses and neuronal health, thereby promoting Alzheimers disease progression

Conversely, excessive copper promotes A aggregation, tau hyperphosphorylation and ROS generation, thereby accelerating neurodegenerative processes (256,257,260)

These routes include: Subcutaneous route that involves the delivery of medications into the fatty tissue beneath the skin, as the root word sub indicates beneath and cutaneous represents the skin