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Additionally, in collaboration with the Nanotechnology Characterization Laboratory, their nanoformulations were evaluated for endotoxin analysis, particle size and zeta potential, in vitro cellular cytotoxicity, immunological assays, metabolism, and pharmacokinetic studies before actual implementation (documented as NCL201304A report, Additional steps to further develop curcumin nanoformulations for efficient use in clinical settings have been suggested in Expert Opinion section

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Referncias: [1] Iliceto S, Scrutinio D, Bruzzi P, DAmbrosio G, Boni L, Di Biase M, Biasco G, Hugenholtz PG, Rizzon P

The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability