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These cells showed resistance to Bevacizumab in vitro and also had higher levels of AKT phosphorylation

doi: 10.3390/ijms19010316 143 WeiL.MartinJ

Statements Author contributions Writingoriginal draft preparation, revisions, figures, review, and editing DKS, Writingreview, and editing RMH, BP, AP, VKY, DW, AEJ

Currently, some prospective animal studies have begun exploring schemes combining drug administration with advanced biomaterials, yielding positive preliminary results, but their long-term efficacy and safety still require evaluation in larger-scale, in-depth studies