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Calorie Restriction Protects against Contrast-Induced Nephropathy via SIRT1/GPX4 Activation

More specifically, previous work has identified increased AGE content and reduced collagen turnover in high strain, frequently injured tendons (equine SDFT) compared to low strain, infrequently injured tendons (equine common digital extensor tendon) (Thorpe et al ., 2010b), reinforcing a potential relationship between loading environment and diet-induced AGE accumulation