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Contraindicated for: Individuals with known allergies to the minerals included

Laboratory-accreditation signals such as ISO/IEC 17025 for the testing lab and cGMP for the manufacturer were treated as strong positives

In addition, treatment effects estimated using MMRM analyses are typically larger than those seen with MI analyses since the MMRM estimates the treatment effect while participants are adhering to the investigational drug, whereas MI-based estimates (reflecting the intent-to-treat approach) are irrespective of adherence

In manufacturing, CanSinoBIO has implemented a safer production process featuring animal component-free fermentation media and phenol-free purification technology, thereby eliminating risks associated with animal-derived materials and toxic residues while preserving vaccine immunogenicity.