g6pd deficiency glutathione Glucose 6 Phosphate Dehydrogenase (G6PD) G6PD Deficiency • Glucose-6-phosphate dehydrogenase

G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No Glucose 6 Phosphate Dehydrogenase deficiency G6PD deficiency, features, Offending & Safe drugs Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Figure 1. G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea Journal of Neuroscience

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