glutathione peroxidase and glutathione reductase The antioxidant role of cellular GSH. (GPX) General reaction mechanisms for antioxidant

These include its comparatively high utilization of oxygen and therefore generation of free radical byproducts, its modest antioxidant defenses, its lipid-rich constitution that provides substrates ready for oxidation, the reducing potential of certain neurotransmitters, and the presence of redox-catalytic metals, like iron and copper (47)

Despite its critical importance to human health, supplementing with glutathione has historically been fraught with challenges

Reasons for this may involve, in addition to the partially better sensitivity of ELISA, cross-reactivity of the applied antibodies with ZEN metabolites as well as other breast milk constituents

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