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10.3389/fphar.2023.1116558 496 YaoY.QiX.JiaY.YeJ.ChuX.WenY.et al

Additionally, it suppresses the antiapoptotic protein Bcl-2 and upregulates the proapoptotic protein Bax, thereby inhibiting abnormal thyroid cell proliferation (101)

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18 Unlike some other copper containing compounds like copper chloride or copper acetate, GHK-Cu has not been found to be cytotoxic or to cause irritation topically, making it an ideal option for delivery of copper into the skin