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Epimedium polysaccharide alleviated P.g -aggravated gut dysbiosis and intestinal inflammation by directly inhibiting the pathogens growth and virulence, restoring beneficial gut genera ( Akkermansia, Bifidobacterium ), and suppressing the pro-inflammatory Th17 pathway ( Rothia and gut Oscillospira ) while decreasing pathogenic ones, thereby relieving inflammation via the oral-gut axis (Wu et al., 2025)

Titrate biotin CNS Penetration Test the penetration test is to determine whether the B12s are entering the cerebrospinal fluid

Thus, we next administered the solution of A monomers, which had been incubated in vitro with a stoichiometric concentration (1:1) of the A-anticalin for 90120 min (Fig