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To cope with the considerable and variable dissimilarity between the composition of the blood and the extracellular compartment of the brain, the central nervous system (CNS) is also shielded from the general blood circulation by a number of blood-CNS barriers, i.e

Other relevant TMA precursors are the products of dietary phosphatidylcholine, choline and betaine 14 , as well as dietary sources such as L-carnitine and ergothioneine 15

Clezardin P, Benzaid I, Croucher PI

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