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Cell 163 (6), 14841499

CostaMLosada-BarreiroSPaiva-MartinsFBravo-DazC

doi: 10.1159/000096554

Therefore, by activating this NCOA4-mediated ferritinophagy pathway, Erastin promotes the release of free iron, which in turn amplifies ROS production and lipid peroxidation, resulting in an autophagy-dependent mode of ferroptosis