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When treating infections caused by Streptococcus pyogenes, therapy should be continued for at least 10 days

It acts as a cofactor for two critical enzymes: methionine synthase, which is involved in DNA methylation and homocysteine metabolism, and methylmalonyl-CoA mutase, which participates in fatty acid metabolism

In a report published Wednesday in the New England Journal of Medicine, researchers with Pfizer and the University of Texas Medical Branch created a version of the virus that carried the same mutations found in the South African variant dubbed B.1.35.1