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Another class of drugs has been explored for PD management is histone deacetylase 6 (HDAC6) inhibitors such as such as CAY10603 and Tubastatin A which enhance the -synuclein aggregates clearance to mitigate neurodegeneration 17,62

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[36] Fpr4 is the prolyl isomerase enzyme (PPIase) which converts the amino acid proline (P) on histones between the cis and trans conformations

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