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In essence, each component supports different steps of metabolic pathways, for example, energy generation from carbohydrates and fats requires B, B, B, and B in sequence

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As we age, mitochondrial function can decline, leading to reduced energy production and a metabolic slowdown

GPX4, once activated, is capable of converting GSH to oxidized GSSG and reducing toxic lipid peroxides (L-OOH) to non-toxic lipid alcohols (L-OH), suggesting that GSH is an essential protective metabolite against ferroptosis (Hwang et al., 2021)