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The lipid peroxidation is a free radical-driven reaction that primarily affects polyunsaturated fatty acids (PUFAs) in cell membranes, the product of which gradually increases during the ferroptotic cell death, from the initial lipid hydroperoxides (LOOHs) to the later production of malondialdehyde (MDA) and 4-hydroxynenoal (Kagan et al., 2017)

The nuclear p50 ATF6 forms homodimers or heterodimers with its homolog ATF6 (84) and both of them can associate with nuclear transcription factor Y (NF-Y) to form transcriptional complexes (85)

Biomed Pharmacother = Biomed Pharmacotherapie (2018) 106:1098107

africanus has a very restricted geographic distribution