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Conflict of interest Trent Stellingwerff, Peter Peeling, Laura Garvican-Lewis, Rebecca Hall, Anu Koivisto, Ida Heikura and Louise Burke have no conflicts of interest relevant to the content of this article

PLoS One 14:e0211540

This finding provides the first evidence of such sex-dependent strategies in H

ER stress blocks the expression of CYP7A1, the rate-limiting step in the synthesis of bile acids through the classic pathway, causing the reprogramming of bile acid metabolism from the classic to the alternative pathway