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doi: 10.1038/ni.3023 93 SutherlandTERckerlDLoganNDuncanSWynnTAAllenJE

To understand further, we observed the induction of mitochondrial genes Bax, and thus involving intrinsic pathways of apoptosis

doi: 10.1016/j.conb.2021.01.002, 9

sALS and fALS progression is clinically and pathologically very similar, both characterized by the progressive accumulation of toxic misfolded protein aggregates within cells [76] and the significant loss of MNs [77]