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605 Substantial preclinical evidence supports the neuroprotective effects of GLP-1R agonists on cognition in AD, which is attributed to the ability to reduce A pathology, tau phosphorylation, glial activation, and neuroinflammation

Depression has not been established as a typical cagrilintide effect from the limited public evidence, but any new or worsening mood symptom matters

The work was supported by the Senior Research Fellowships to SS from UGC (University Grants Commission) and JSA and SM from CSIR (Council of Scientific and Industrial Research), New Delhi, India