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4.2 Recovering mitochondrial dysfunction Mitochondrial dysfunction not only drivers ferroptostic process but promotes SLE progression

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10.1016/S0140-6736(05)17706-X 135 WeizmanZ.Abu-AbedJ.BinsztokM

[63] found that the enzyme dihydroorotate dehydrogenase (DHODH) and mitochondrial GPX4 constitute two additional defense enzymes that can detoxify lipid peroxides in the mitochondria