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Additionally, ACOs that did not meet the quality performance standard as specified under 425.512, or were subject to a pre-termination action from CMS after determining that the ACO had avoided at-risk beneficiaries, as specified under 425.316(b)(2), in the agreement period preceding the agreement period in which the ACO would receive prepaid shared savings, would be prohibited from participating in the prepaid shared savings payment option, as these compliance issues could prevent an ACO from earning shared savings that would be used to repay the prepaid shared savings

By blocking these enzymes, ibuprofen effectively "turns off" the pain signals and reduces swelling

Isolate the variable to be sure

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