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The mechanism is to promote the GSH levels and reduce MDA, lipid peroxidation, and mitochondrial reactive oxygen ROS ( 3.5 Hormones and novel regulatory factors The suppression of interferon regulatory factor 9 (IRF9) enhances the differentiation of osteoclasts, consequently hindering ferroptosis and potentially offering a new avenue for the treatment of osteoporosis ( in vivo and in vitro ( 3.6 Advanced delivery systems targeting ferroptotic hubs Although the research on natural ingredients combined with advanced delivery systems is limited, it is still an innovation and a future research direction

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on cell death 2012

Current Chemical Biology, 8(1), 1522