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Oral formulations, in particular, have shown promise in treating arthritis and neurodegenerative disorders, with good tolerability and minimal gastrointestinal side effects

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

and any medical, neurological, or psychiatric disorder that could reasonably be expected to interfere with the assessment of MS symptoms, or with the study assessments including the FDG PET imaging