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As a close structural relative of GHK-Cu (Gly-His-Lys), AHK-Cu shares the copper-chelating tripeptide architecture but exhibits a distinct biological activity profile studied particularly in the contexts of hair follicle biology, angiogenesis, and skin extracellular matrix research

This effect is related to the synthesis of nerve myelin lipids and the maintenance of the integrity of sheathed nerve fibers

Amelioration of Cyp7a1 and G6pc by fat transplantation in Insr P1195L/ +/HFD liver and suppression of Cyp7a1 by glycerol in wild-type mice suggest that suppressed hepatic expression of Cyp7a1 might well play a role in the regulation of glucose homeostasis in Insr P1195L/ +/HFD mice

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