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Pathway analysis classified genes regulated by caffeine as being involved in chemokine signaling, cytokine-cytokine receptor interaction, phagosome, ECM-receptor interaction, PI3K-AKT signaling, MAPK signaling, Toll-like receptor signaling, NOD-like receptor signaling, NF-kappa B signaling, and others

Hyperhomocysteinemia is associated with inflammation, bone resorption, vitamin B12 and folate deficiency and MTHFR C677T polymorphism in postmenopausal women with decreased bone mineral density

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