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In mouse models, CD5+ B cells have been shown to belong to a B1a subset that is typically located in the peritoneum and produces low-affinity autoreactive IgM antibodies (47)

10.1038/s41568-019-0135-7 Nat

While FDAs response is extensive, its arguments boil down to two key points: (1) While the 2018 Farm Bill modified how CBD is regulated, it did not alter its regulatory status as a New Dietary Ingredient

While this case study focuses on a rare epilepsy caused by a KCNC2 mutation, there are over 100 potassium channel genes, many of which are potential candidates for similar gain-of-function mutations