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However, the OS benefit is questioned by some experts because of deaths unrelated to treatment or disease and because 31 % of FCR patients did not complete all six treatment cycles

pneumoniae infects endothelial cells, smooth-muscle cells and monocytes/macrophages, and induces inflammatory reactions that are commonly observed in atherosclerosis

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Another real-world study assessing discontinuation rates in patients on DTG-based regimens revealed that 13.7% of participants discontinued treatment due to intolerance, primarily due to neuropsychiatric symptoms such as sleep disturbances, anxiety, and depression ( Although CCR5 antagonists (e.g., Maraviroc), post-attachment inhibitors (e.g., Ibalizumab), and capsid inhibitors (e.g., Lenacapavir) hold significant therapeutic value in specific populations, their clinical use remains limited by targeted indication requirements and high treatment costs