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Thus, preincubation with the glutathione inhibitor buthionine sulfoximine (BSO) induced massive cell death, whereas N -acetyl cysteine, a precursor of glutathione synthesis, improved the resistance to cisplatin treatment

Predicting tumor cell line response to drug pairs with deep learning

The resulting complex can regulate gene activity by binding directly to DNA regulatory elements called estrogen response elements (EREs), leading to the recruitment of additional factors involved in the regulation of transcription (207)

MSCs can be sourced from various tissues, including the brain, thymus, heart, liver, and lungs, and are easily expanded in culture, making them ideal candidates for transplantation