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Often used in beauty supplements for its skin-lightening and anti-aging effects

The mutant enzyme mischarges tRNAAla with Gly or Ser, leading to amino acid misincorporation and protein misfolding, causing cerebellar Purkinje cell loss and ataxia, but not peripheral axon degeneration

10.1164/rccm.201305-0908LE Am J Respir Crit Care Med

Ultrasound Obstet Gynecol 54(3):297307 Lucas D, Menez C, Girre C, Berthou F, Bodenez P, Joannet I et al (1995) Cytochrome P450 2E1 genotype and chlorzoxazone metabolism in healthy and alcoholic Caucasian subjects