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Reported side effects are typically mild: Morning grogginess: Uncommon, usually associated with initial dosing or timing adjustments Vivid dreams: Some patients report more vivid dreams, which may reflect enhanced REM sleep Headache: Occasionally reported, usually mild and transient Injection site reactions: Minor redness or discomfort at the injection site DSIP has not demonstrated significant interactions with common medications in published studies

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and the replacement of norleucine with a non-ot-amino acid -aminobutyric acid (GAB A)