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Not all of these steps from oxidative attack to final hemolysis have been fully documented in vivo, in part because of one major difficulty: in the course of AHA the red blood cells sampled from the patient are obviously, at any given stage, those that have not yet hemolyzed

Indeed, the prognoses of patients carrying NRF2-positve cancers are significantly poor (Shibata et al., 2008b

(B) 8226/S, 8226/S-CR, 8226/S-ATOR05 control cells, as well as control cells from the indicated time points were harvested and the intracellular GSH concentration was determined as described in the Materials and Methods