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In general, most upregulated non-receptor kinases are implicated in defense signaling such as EDR (Hiruma et al., 2011), and cellular development and expansion like M3KE1 (Sakai et al., 2008) ( Supplement Table 5 )

Keywords utilized in this search included Nrf2/KEAP1 signaling pathway, inflammation, apoptosis, antioxidant, oxidative stress, mastitis, and bioactive compounds, with a focus on their antioxidant and anti-inflammatory properties

Leyme, A., Marivin, A., Casler, J., Nguyen, L

The study documented dose-dependent IGF-1 increases reaching 1.5-3 fold above baseline with effects persisting for up to 2 weeks