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Description

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

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For patients following a vegetarian or vegan diet , the risk of B12 deficiency is compounded further, as plant-based foods contain no naturally occurring B12

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These include the bell-shaped dose-response curve, central effects after peripheral administration, a delayed and prolonged time course, and some penetration of the blood-brain barrier in essentially intact form

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proposed that 1-MNA is a methylation sink (88)

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