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Taken together, these data suggest that combined inhibition of GLUT1 and GCL mimics glucose deprivation-induced cell death

In 2015, the FDA addressed the concerns with a Safety Communication stating that it is safe and that the studies showing that it wasnt safe were all flawed.[ref] Lets take a look at some of the studies and then dig into the mechanism of action

Future research must move beyond the simplistic paradigm of inhibition equals benefit toward spatiotemporally precise, cell type-specific, pathway-integrated, and biomarker-guided strategies