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Some studies were conducted to investigate the single- and multiple-dose pharmacokinetics of chelerythrine (CHE) and its metabolite in animals

(2010) 93:S21626

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Catalytic Residues Roles Chemical Components aromatic unimolecular elimination by the conjugate base, hydride transfer, aromatic bimolecular nucleophilic addition, cofactor used, intermediate formation, overall product formed, overall reactant used, rate-determining step, bimolecular nucleophilic substitution, enzyme-substrate complex formation, enzyme-substrate complex cleavage, intermediate collapse, intermediate terminated, native state of cofactor regenerated, proton transfer, native state of enzyme regenerated References Deponte M (2013), Biochim Biophys Acta , 1830 , 3217-3266