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Description

Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster

210 Neurofibrillary tangles gradually accumulate in the brain and are closely related to the prevalence of AD and the degree of disease

In immature neurons (5-6 weeks post-differentiation), volcano plot analysis identified a marked upregulation of SDSL (Serine Dehydratase-Like), a key enzyme in serine metabolism, as well as FPGT, a glycosylation-related protein (Fig.5a)