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Additionally, other pathways such as the Hodge, Wolff, and acetyl alcohol pathways also contribute to AGE formation, often involving free radicals and metal ions

Cell 73, 354363.e3

The latter is a major antioxidant and plays an important role in the maintenance of the redox status of the cell and in protecting against oxidative damage by reactive oxygen species (Wang and Ballatori, 1998)

The prognostic role of obesity is independent of sex in cancer patients treated with immune checkpoint inhibitors: a pooled analysis of 4090 cancer patients