glutathione skin whitening effectiveness evidence as a skin‐lightening agent and in melasma: a systematic review - Sarkar - 2025 - International Journal of Dermatology Glutathione Injection: Benefits, After Care

Cannabidiol has been suggested as a promising therapeutic agent for the treatment of acne vulgaris because it normalizes the lipogenesis of sebocyte cells, decreases the proliferation of these cells, and decreases the levels of pro-inflammatory cytokines [105,110,129]

Further research demonstrates synthetic curcumins ability (0.22 g/mL) to modulate T-cell-mediated inflammation by restraining CD4+ T-cell proliferation induced by CD2/CD3/CD28, regulating CD69, CCR7, L-selectin, and TGF1 expression depending on the phase of the T cell activation [57]

This process is inhibited by chloroquine (CQ) and amodiaquine (AQ) [13], leading to an intensive discussion about the role of oxidative stress in the mechanism of action of 4-aminoquinolines [14], [15], [16]

It would therefore be interesting in future experiments to follow the levels of GSLs and their degradation products in plants exposed to ITC for a longer period of time