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IGF-1 (Insulin-like Growth Factor 1) is a crucial growth factor that works in close association with Growth Hormone (GH) to regulate cell growth, repair, and metabolism

Structurally, NRF1 contains a DNA-binding domain (DBD) that recognizes guaninecytosine (GC)-rich sequences, a dimerization domain (DD), and a C-terminal transactivation domain (TAD)

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