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Expert Opin Drug Metab Toxicol 20(4):235248

Aflatoxin B 1 metabolism: regulation by phase I and II metabolizing enzymes and chemoprotective agents

Similarly, immunotherapy promotes non-proliferative yet aggressive dedifferentiated phenotypes via microenvironmental stresses, including tumor-derived inflammasomes, stimulator of interferon genes (STING)/type I interferon signaling, methionine depletion, taurine overproduction, and dysregulated cytokine networks [95, 96]